Cyclin-Dependent Kinase Inhibitors and Human Cancer

作者: A. Kamb

DOI: 10.1007/978-3-642-71941-7_7

关键词:

摘要: As tumor suppressor candidates, cyclin-dependent kinase (CDK) inhibitors have a simple, aesthetic quality. They act directly on the mechanism that drives cells through mitosis and DNA replication. Elimination of CDK inhibitor activity, by mutation for instance, should release CDKs from this form regulation remove one restraints cell growth.

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