作者: A. Kamb
DOI: 10.1007/978-3-642-71941-7_7
关键词:
摘要: As tumor suppressor candidates, cyclin-dependent kinase (CDK) inhibitors have a simple, aesthetic quality. They act directly on the mechanism that drives cells through mitosis and DNA replication. Elimination of CDK inhibitor activity, by mutation for instance, should release CDKs from this form regulation remove one restraints cell growth.