Germline p16 mutations in familial melanoma.
作者： Christopher J. Hussussian , Jeffery P. Struewing , Alisa M. Goldstein , Paul A. T. Higgins , Delphine S. Ally
DOI: 10.1038/NG0994-15
关键词: Germline 、 Biology 、 Cancer research 、 Missense mutation 、 Germline mutation 、 Hereditary Melanoma 、 Melanoma 、 Gene mapping 、 Genetic heterogeneity 、 Chromosome 、 Genetics
摘要: The p16 gene is located in chromosome 9p21, a region that is linked to familial melanoma and homozygously deleted in many tumour cell lines. We describe eight p16 germline …
nature.com
sci-hub.se 参考文章(25)
J L Bolognia, T L Yang-Feng, E M Petty, L H Gibson, A E Bale, J W Fountain, D E Housman, Molecular definition of a chromosome 9p21 germ-line deletion in a woman with multiple melanomas and a plexiform neurofibroma: implications for 9p tumor-suppressor gene(s). American Journal of Human Genetics. ,vol. 53, pp. 96- 104 ,(1993)
O W McBride, K S Kearns, E C Ho, S J Bale, M A Tucker, M C Fraser, W H Clark, A M Goldstein, N C Dracopoli, Further evidence for a locus for cutaneous malignant melanoma-dysplastic nevus (CMM/DN) on chromosome 1p, and evidence for genetic heterogeneity. American Journal of Human Genetics. ,vol. 52, pp. 537- 550 ,(1993)
Richard F. Kefford, Derek J. Nancarrow, Graham J. Mann, Graeme J. Walker, Jane M. Palmer, Marilyn K. Walters, Jennifer A. Donald, Nicholas K. Hayward, Sharon C. Beaton, Catherine Luxford, James L. Weber, Elizabeth A. Holland, Jane W. Fountain, Confirmation of chromosome 9p linkage in familial melanoma American Journal of Human Genetics. ,vol. 53, pp. 936- 942 ,(1993)
J Ott, G M Lathrop, J M Lalouel, C Julier, Multilocus linkage analysis in humans: detection of linkage and estimation of recombination. American Journal of Human Genetics. ,vol. 37, pp. 482- 498 ,(1985)
A. M. Goldstein, M. Engelstein, N. C. Dracopoli, M. A. Tucker, M. C. Fraser, W. H. Clark, Linkage of cutaneous malignant melanoma/dysplastic nevi to chromosome 9p, and evidence for genetic heterogeneity. American Journal of Human Genetics. ,vol. 54, pp. 489- 496 ,(1994)
Jane W Fountain, Thomas J Hudson, Marcy Engelstein, David E Housman, Nicholas C Dracopoli, Jane W Fountain, Thomas J Hudson, Marcy Engelstein, David E Housman, Nicholas C Dracopoli, Dinucleotide repeat polymorphism at the D9S126 locus (9p21) Human Molecular Genetics. ,vol. 2, pp. 823- 823 ,(1993) , 10.1093/HMG/2.6.823-A
R. Day, B. Johnson, M. Skolnick, A Kamb, N. Gruis, J Weaver-Feldhaus, Q Liu, K Harshman, S. Tavtigian, E Stockert, A cell cycle regulator potentially involved in genesis of many tumor types Science. ,vol. 264, pp. 436- 440 ,(1994) , 10.1126/SCIENCE.8153634
Sherri J. Bale, Nicholas C. Dracopoli, Margaret A. Tucker, Wallace H. Clark, Mary C. Fraser, Ben Z. Stanger, Philip Green, Helen Donis-Keller, David E. Housman, Mark H. Greene, Mapping the gene for hereditary cutaneous malignant melanoma-dysplastic nevus to chromosome 1p The New England Journal of Medicine. ,vol. 320, pp. 1367- 1372 ,(1989) , 10.1056/NEJM198905253202102
CEDRIC A. B. SMITH, TESTING FOR HETEROGENEITY OF RECOMBINATION FRACTION VALUES IN HUMAN GENETICS. Annals of Human Genetics. ,vol. 27, pp. 175- 182 ,(1963) , 10.1111/J.1469-1809.1963.TB00210.X
A. W. F. Edwards, J. Ott, Analysis of Human Genetic Linkage. Biometrics. ,vol. 43, pp. 254- ,(1987) , 10.2307/2531972