摘要: Publisher Summary This chapter discusses the immunoregulation by antibody. The immunosuppressive effects of antibody have been attributed to either a peripheral or central mechanism. A mechanism implies an action on potentially immunogenic sites antigen and indicates effect antibody-forming cells their precursors. evidence strongly that both mechanisms operate, perhaps not simultaneously, certainly under all experimental conditions. discovery synthesis IgM can be halted passive immunization with IgG provided new dimension concept accounted for transient appearance antibodies after stimulation many kinds antigens. It has demonstrated leads production high affinity once administered worn off. comes about because selective pressure diminishing concentration preferentially recruits immunocompetent receptors antigen.