Immunoregulation by Antibody

作者: ROBERT S. SCHWARTZ

DOI: 10.1016/B978-0-12-057550-3.50082-X

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摘要: Publisher Summary This chapter discusses the immunoregulation by antibody. The immunosuppressive effects of antibody have been attributed to either a peripheral or central mechanism. A mechanism implies an action on potentially immunogenic sites antigen and indicates effect antibody-forming cells their precursors. evidence strongly that both mechanisms operate, perhaps not simultaneously, certainly under all experimental conditions. discovery synthesis IgM can be halted passive immunization with IgG provided new dimension concept accounted for transient appearance antibodies after stimulation many kinds antigens. It has demonstrated leads production high affinity once administered worn off. comes about because selective pressure diminishing concentration preferentially recruits immunocompetent receptors antigen.

参考文章(52)
H. Wigzell, Use of humoral or cellbound antibody to achieve depression of immunological reactivity. Antibiotics and Chemotherapy. ,vol. 15, pp. 82- 97 ,(1969) , 10.1159/000386773
Jonathan W. Uhr, Göran Möller, Regulatory effect of antibody on the immune response. Advances in Immunology. ,vol. 8, pp. 81- 127 ,(1968) , 10.1016/S0065-2776(08)60465-4
Leo Olitzki, The Antigenic Properties of Bacteria Combined with Antibodies Journal of Immunology. ,vol. 29, pp. 453- 465 ,(1935)
Sidney Schneck, Gregory W. Siskind, Henry Chang, Alice Deutsch, Neil I. Brody, Studies on the Mechanism of the Suppression of Active Antibody Synthesis by Passively Administered Antibody Journal of Immunology. ,vol. 102, pp. 37- 41 ,(1969)
Patricia J. McConahey, Jean-Charles Cerottini, Frank J. Dixon, The Immunosuppressive Effect of Passively Administered Antibody IgG Fragments Journal of Immunology. ,vol. 102, pp. 1008- 1015 ,(1969)