Avian Acute Leukemia Viruses

摘要: On the basis of their oncogenic properties, avian retroviruses can be divided into three groups: (a) sarcoma viruses (ASV), which cause solid tumors connective tissue after a short latency period; (b) lymphatic leukemia (LLV), B-cell lymphoma only long period approximately 6 months or more; and (c) acute (ALV), upon infection young chickens rapidly bring about death birds from variety different neoplasms, usually, but not exclusively, hematopoietic system (Purchase Burmester 1973; Hanafusa 1977; Graf Beug 1978). This classification is absolute, in that there are overlaps spectra these viruses. For example, certain LLV have been shown to erythroblastosis occasionally sarcomas 1973); similarly, ALV also (Rothe-Meyer Engelbreth Holm 1933; et al. 1977). However, by using this seven field isolates listed Table 1 grouped together as There another isolate, reticuloendothelosis virus (REV-T), is, definition, an ALV; however, since it related classical leukosis/sarcoma complex judged nucleic acid homology, will included here. Interested readers referred Witter (1978) Stehelin (1982). numerous reports literature regarding isolation other unfortunately, strains no longer available (see Consequently, considered review.