SNP frequency, haplotype structure and linkage disequilibrium in elite maize inbred lines

作者: Ada Ching , Katherine S Caldwell , Mark Jung , Maurine Dolan , Oscar Smith

DOI: 10.1186/1471-2156-3-19

关键词:

摘要: Background Recent studies of ancestral maize populations indicate that linkage disequilibrium tends to dissipate rapidly, sometimes within 100 bp. We set out examine the and diversity in elite inbred lines, which have been subject population bottlenecks intense selection by breeders. Such events are expected increase amount disequilibrium, but reduce diversity. The results this study will inform design genetic association studies.

参考文章(53)
S. J. Wall, H. Sullivan, O. S. Smith, B. Hobart, Evaluation of a divergent set of SSR markers to predict F1 grain yield performance and grain yield heterosis in maize. Maydica. ,vol. 45, pp. 235- 241 ,(2000)
Dinakar Bhattramakki, Maureen Dolan, Mike Hanafey, Robin Wineland, Dave Vaske, James C. Register III, Scott V. Tingey, Antoni Rafalski, Insertion-deletion polymorphisms in 3' regions of maize genes occur frequently and can be used as highly informative genetic markers. Plant Molecular Biology. ,vol. 48, pp. 539- 547 ,(2002) , 10.1023/A:1014841612043
Mark J. Daly, John D. Rioux, Stephen F. Schaffner, Thomas J. Hudson, Eric S. Lander, High-resolution haplotype structure in the human genome. Nature Genetics. ,vol. 29, pp. 229- 232 ,(2001) , 10.1038/NG1001-229
Jeffry M. Thornsberry, Major M. Goodman, John Doebley, Stephen Kresovich, Dahlia Nielsen, Edward S. Buckler, Dwarf8 polymorphisms associate with variation in flowering time Nature Genetics. ,vol. 28, pp. 286- 289 ,(2001) , 10.1038/90135
Gabor T. Marth, Ian Korf, Mark D. Yandell, Raymond T. Yeh, Zhijie Gu, Hamideh Zakeri, Nathan O. Stitziel, LaDeana Hillier, Pui-Yan Kwok, Warren R. Gish, A general approach to single-nucleotide polymorphism discovery Nature Genetics. ,vol. 23, pp. 452- 456 ,(1999) , 10.1038/70570
J L Weber, P E May, Abundant class of human DNA polymorphisms which can be typed using the polymerase chain reaction American Journal of Human Genetics. ,vol. 44, pp. 388- 396 ,(1989)
Neil J. Risch, Searching for genetic determinants in the new millennium Nature. ,vol. 405, pp. 847- 856 ,(2000) , 10.1038/35015718
Gillian C.L. Johnson, Laura Esposito, Bryan J. Barratt, Annabel N. Smith, Joanne Heward, Gianfranco Di Genova, Hironori Ueda, Heather J. Cordell, Iain A. Eaves, Frank Dudbridge, Rebecca C.J. Twells, Felicity Payne, Wil Hughes, Sarah Nutland, Helen Stevens, Phillipa Carr, Eva Tuomilehto-Wolf, Jaakko Tuomilehto, Stephen C.L. Gough, David G. Clayton, John A. Todd, Haplotype tagging for the identification of common disease genes Nature Genetics. ,vol. 29, pp. 233- 237 ,(2001) , 10.1038/NG1001-233
Handbook of statistical genetics John Wiley & Sons (2001). ,(2004) , 10.1002/0470022620