A general approach to single-nucleotide polymorphism discovery

作者: Gabor T. Marth , Ian Korf , Mark D. Yandell , Raymond T. Yeh , Zhijie Gu

DOI: 10.1038/70570

关键词: Reference genomeExpressed sequence tagBiologyNucleic acid sequenceSequence alignmentGenetic markerMultiple sequence alignmentGeneticsComputational biologySequence (medicine)Alignment-free sequence analysis

摘要: Single-nucleotide polymorphisms (SNPs) are the most abundant form of human genetic variation and a resource for mapping complex genetic traits 1. The large volume of data …

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