Risk factors and gene expression in esophageal cancer.
作者： Xiao-chun Xu
DOI: 10.1007/978-1-59745-416-2_17
关键词:
摘要: Esophageal cancer is a significant worldwide health problem because of its poor prognosis and high incidence in certain parts the world. Tobacco smoke alcohol consumption are risk factors for esophageal squamous cell carcinoma, whereas frequent gastroesophageal reflux subsequent inflammatory reactions play role causing adenocarcinoma. carcinogenesis involves multiple genetic alterations. A large body knowledge has been generated regarding molecular alterations associated with carcinogenesis. These include aberrant cycle control, DNA repair, cellular enzymes, growth factor receptors, nuclear receptors. This chapter reviews most gene their correlation as well prevention strategies cancer.
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