UNIVERSIDADE FEDERAL DO RIO GRANDE DO SUL FACULDADE DE VETERINÁRIA PROGRAMA DE PÓS–GRADUAÇÂO EM CIÊNCIAS VETERINÁRIAS EFEITOS DA METIONINA E DA ARGININA SOBRE A RESPOSTA IMUNE E O DESEMPENHO DE FRANGOS DE CORTE

作者: Ana Paula Ravazzolo , Lauricio Librelotto Rubin , Frangos De Corte , Andréa Machado Leal

DOI:

关键词:

摘要: Our knowledge of nutrition poultry and livestock is relatively mature, including a very complete listing the required nutrients, quantitative accounting minimal level each nutrient that needed to maximize production characteristics, levels bioavailabilities essential nutrients supplied by feedstuffs. However, it not known if requirement values productivity in healthy, unchallenged animals are optimal for immunocompetence disease resistance. The regulation substract availability (diet nutrients) one mechanisms trough witch interferes on immune response. Amino acids like methionine arginine two examples this. Methionine important protein synthesis, glutathione polyamines principal source metil groups DNA formation. Arginine nitric oxide macrophages. Nitric has bactericide action, playing role cellular citotoxic activity. This study aim evaluate influence supplementation at different performance response broiler chickens immunologically stimuli. First experiment evaluated (as sulfur amino – SAA). In initial fase (1 21 days) tested were 0.72, 0.82 0.92% final (22 42 0.65, 0.75 0.85%. stimuli program was constituted vaccines routinely adopted large-scale bird husbandry, inactivated Mycobacterium avium avian tuberculin. As results SAA influenced Yet, administered impaired upon day age. total period an interaction between immunological observed, this greatest ASS no-stimulated group showed better weight gain. second (0.31, 0.51 0.66% phase 0.29, 0.49 0.64% phase) (1.33 1.83% 1.14 1.64% avium, Sheep Red Blood Cells 10% (SRBC), It observed neither nor To methionine, no effect humoral response, however intermediate caused Moreover, first Based these experiments it’s possible conclude here similar those used current could be adequate attend system requirements. practical increased god sanity used. see vaccination programs necessary but certainly interfere negative way.

参考文章(132)
R J Huxtable, Taurine. Past, present, and future Advances in Experimental Medicine and Biology. ,vol. 403, pp. 641- 650 ,(1996)
A.E. HARPER, Amino Acid Toxicities and Imbalances Mammalian Protein Metabolism#R##N#Volume II. pp. 87- 134 ,(1964) , 10.1016/B978-1-4832-3210-2.50009-1
Anne-Marie Lebacq-Verheyden, J. P. Vaerman, J. F. Heremans, A possible homologue of mammalian IgA in chicken serum and secretions. Immunology. ,vol. 22, pp. 165- ,(1972)
D. Breuille, F. Rose, M. Arnal, C. Melin, C. Obled, Sepsis modifies the contribution of different organs to whole-body protein synthesis in rats. Clinical Science. ,vol. 86, pp. 663- 669 ,(1994) , 10.1042/CS0860663
S. Shini, W. L. Bryden, X. Li, Methionine requirement and cell-mediated immunity in chicks. 29th Annual Scientific Meeting of the Nutrition Society of Australia. ,vol. 14, pp. 123- 123 ,(2005)
R.B. Burns, Histology and immunology of Peyer's patches in the domestic fowl (Gallus domesticus). Research in Veterinary Science. ,vol. 32, pp. 359- 367 ,(1982) , 10.1016/S0034-5288(18)32396-8
T. W. F. Göbel, C. H. Chen, M. D. Cooper, Avian Natural Killer Cells Current Topics in Microbiology and Immunology. ,vol. 212, pp. 107- 117 ,(1996) , 10.1007/978-3-642-80057-3_10
B. G. Bang, F. B. Bang, Localized lymphoid tissues and plasma cells in paraocular and paranasal organ systems in chickens. American Journal of Pathology. ,vol. 53, pp. 735- 751 ,(1968)
Anders Larsson, David Carlander, Resistance and various kinds of immunity in birds Mathew. pp. 48- ,(2002)