Agonists for antimicrobial peptide systems

作者: Rubhana Raqib , Birgitta Agerberth , Roger Stromberg , Eirikur Steingrimsson , Gudmundur Hrafn Gudmundsson

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摘要: Short chain fatty acids (SCFAs) and glycerol esters of SCFAs not previously used for that purpose are provided use as a medicament treating, preventing or counteracting microbial infections in animals, including humans, by stimulating the innate antimicrobial peptide defense system. Preferred compounds include phenyl substituted short derivatives and. Also methods compositions infections, bacterial, viral, fungal, parasitic administration medicaments comprising secretagogue-effective amount invention.