Low expression of microRNA-204 (miR-204) is associated with poor clinical outcome of acute myeloid leukemia (AML) patients.
作者： Aleksandra Butrym , Justyna Rybka , Dagmara Baczyńska , Andrzej Tukiendorf , Kazimierz Kuliczkowski
DOI: 10.1186/S13046-015-0184-Z
关键词:
摘要: Background Acute myeloid leukemia (AML) is a heterogeneous neoplasm of the bone marrow with poor prognosis. In clinical practice new prognostic factors are still needed. MicroRNAs (miRs), small endogenous noncoding RNAs, play an essential role in development and progression acute leukemia. The aim study was to evaluate miR-204 expression patients AML at diagnosis after induction chemotherapy, comparison healthy controls. We also investigated, if correlates features patients.
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