Occipital nerve stimulation for the treatment of intractable chronic migraine headache: ONSTIM feasibility study.
作者： Joel R Saper , David W Dodick , Stephen D Silberstein , Sally McCarville , Mark Sun
关键词:
摘要: Background: Medically intractable chronic migraine (CM) is a disabling illness characterized by headache ≥15 days per month. Methods: A multicenter, randomized, blinded, controlled feasibility study was conducted to obtain preliminary safety and efficacy data on occipital nerve stimulation (ONS) in CM. Eligible subjects received an block, responders were randomized adjustable (AS), preset (PS) or medical management (MM) groups. Results: Seventy-five of 110 assigned treatment group; complete diary available for 66. responder defined as subject who achieved 50% greater reduction number month three-point average overall pain intensity compared with baseline. Three-month rates 39% AS, 6% PS 0% MM. No unanticipated adverse device events occurred. Lead migration occurred 12 51 (24%) subjects. Conclusion: The results this offer promise should prompt further studies ONS
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