Plasma selenoprotein P levels of healthy males in different selenium status after oral supplementation with different forms of selenium.

摘要: Objective: To assess changes in selenoprotein P levels plasma from subjects who had received oral supplements of different selenium forms. Design: The same study group participated two similar supplementation trials, Trial I 1981 () and II 1987 (). During the mean baseline intake Finland was higher compared to that during (100 40 μg/d, respectively), due a nation-wide fertilisers which started 1985. Subjects: Fifty healthy Finnish men, 36–60 y old. Intervention: daily placebo or consisting 200 μg as selenium-enriched yeast, sodium selenate wheat (Trial I) selenite II). duration periods 11 16 II) weeks. Results: In values all supplemented groups increased significantly, approaching plateau at 2 weeks reaching maxima 4 (mean increase 34%, P<0.05). were not significantly each other start any time point period. Conclusions: At low status fashion after with forms selenium, but high no significant effects amount observed. No differences observed for inorganic organic supplements. Sponsorship: This supported by Swedish Council Forestry Agricultural Research, Pahlsson Foundation Nutrition Foundation.