Manage narcolepsy with psychostimulants based on the individual’s most prominent symptoms, medical history and comorbidities

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DOI: 10.1007/S40267-016-0342-1

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摘要: Narcolepsy is a chronic, neurological disorder of sleep–wake cycle dysregulation, for which most patients require lifelong pharmacological therapy. Recommended treatments include modafinil as first-line therapy excessive daytime sleepiness (EDS), and sodium oxybate EDS with cataplexy and/or other associated symptoms (i.e. hypnagogic/hypnopompic hallucinations, sleep paralysis disturbed nocturnal sleep). Behavioural strategies, such taking planned naps maintaining regular night-time schedules, may provide complementary benefits to

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