作者: Bo K. Siesjö
DOI: 10.1016/S0079-6123(08)61980-9
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摘要: Publisher Summary This chapter discusses the current information on brain acid-base metabolism in health and disease. The deals with some of conceptual difficulties applying theory to systems having composition extra- intracellular fluids. features cellular regulation extracerebral tissues are discussed, corresponding pH is described. changes e i disease discussed. considers possible molecular mechanisms, whereby acidosis can cause or aggravate cell injury. describes behavior simulated fluid, two additional equations, describing ionization a weak acid (Ha), conservation mass—that is, constancy total buffer concentration (C),