Compositional and functional features of the female premenopausal and postmenopausal gut microbiota.
作者： Hui Zhao , Juanjuan Chen , Xiaoping Li , Qiang Sun , Panpan Qin
关键词:
摘要: Endogenous estrogen deficiency accelerates many diseases in postmenopausal women, and gut microbes contribute to level modulation. However, the compositional alterations influences of microbiota women remain uncertain. A metagenome-wide association study was performed compare 24 premenopausal women. Firmicutes Roseburia spp. are depleted, while Bacteroidetes toluene-producing genus Tolumonas overrepresented fecal samples from The pentose phosphate pathway is enriched Homocysteine synthesis-related processes microbiomes differ produce different metabolites. microbiome may be a therapeutic target reduce risks improve quality life
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