Permeability decay in CAVH hemofilters.

摘要: Change in hydraulic permeability over time was measured four types of continuous arteriovenous hemofiltration (CAVH) hemofilters order to characterize decay and demonstrate that occurs without membrane protein exposure. Polyamide, polysulfone, polyacrylonitrile were placed a gravity-driven vitro CAVH apparatus. Distilled deionized water or saline used perfuse the hemofilters. A biphasic pattern seen all hemofilter types. large exponential decline occurred first 1 6 hours, with more gradual thereafter. Of membranes studied, polysulfone most permeable upon initiation use but showed pronounced early late decay. Both polyamide little after brief These data suggest may not be primarily due coating. Initial high place some systems at risk for plugging.