Oxygen ion implantation at 20 to 2000 keV into polysulfone for improvement of endothelial cell adhesion.

作者: Guochun Xu , Yutaka Hibino , Yasuo Suzuki , Yoshiaki Suzuki , Kimi Kurotobi

DOI: 10.1016/S0927-7765(00)00161-2

关键词:

摘要: The irradiation effects of oxygen on polysulfone have been investigated at energies 20 keV, 150 keV and 2 MeV. strong improvement endothelial cell adhesion proliferation is found ion irradiated keV. Such declined with increasing energy. changes surface color free energy are strongly dependent dose. formation amorphous carbon phase demonstrated by Raman spectroscopy its degree correspondent to the observed. formations hydroxyl carboxyl groups confirmed attenuated total reflectance (ATR) FTIR spectroscopy. depletions heteroatoms conjectured detail analysis X-ray photoelectron (XPS). Since no single one these can be related directly improved cells surface, we argue that distribution functional crucial in promoting cells. Although cannot detected present, were results TRIM simulation. controlled adjusting size dose irradiating for optimum morphology adhesion.

参考文章(12)
M. Yoshikawa, G. Katagiri, H. Ishida, A. Ishitani, T. Akamatsu, Raman spectra of diamondlike amorphous carbon films Journal of Applied Physics. ,vol. 64, pp. 6464- 6468 ,(1988) , 10.1063/1.342063
B. Pignataro, E. Conte, A. Scandurra, G. Marletta, Improved cell adhesion to ion beam-irradiated polymer surfaces. Biomaterials. ,vol. 18, pp. 1461- 1470 ,(1997) , 10.1016/S0142-9612(97)00090-2
Stephen M. Schwartz, SELECTION AND CHARACTERIZATION OF BOVINE AORTIC ENDOTHELIAL CELLS In Vitro Cellular & Developmental Biology – Plant. ,vol. 14, pp. 966- 980 ,(1978) , 10.1007/BF02616210
J. Rieu, A. Pichat, L-M. Rabbe, A. Rambert, C. Chabrol, M. Robelet, Ion implantation effects on friction and wear of joint prosthesis materials Biomaterials. ,vol. 12, pp. 139- 143 ,(1991) , 10.1016/0142-9612(91)90192-D
J.-B. Lhoest, J.-L. Dewez, P. Bertrand, PMMA surface modification under keV and MeV ion bombardment in relation to mammalian cell adhesion Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms. ,vol. 105, pp. 322- 327 ,(1995) , 10.1016/0168-583X(95)00524-2
Daniel R. Coulter, Mark V. Smith, Fun-Dow Tsay, Amitava Gupta, R. E. Fornes, The effects of 3-MeV proton radiation on an aromatic polysulfone Journal of Applied Polymer Science. ,vol. 30, pp. 1753- 1765 ,(1985) , 10.1002/APP.1985.070300439
Václav Švorčík, Vladimír Rybka, Vladimír Hnatowicz, Lucie Bačáková, Věrá Lisá, František Kocourek, Surface properties and biocompatibility of ion-implanted polymers Journal of Materials Chemistry. ,vol. 5, pp. 27- 30 ,(1995) , 10.1039/JM9950500027
Eric A. Jaffe, Ralph L. Nachman, Carl G. Becker, C. Richard Minick, Culture of Human Endothelial Cells Derived from Umbilical Veins. IDENTIFICATION BY MORPHOLOGIC AND IMMUNOLOGIC CRITERIA Journal of Clinical Investigation. ,vol. 52, pp. 2745- 2756 ,(1973) , 10.1172/JCI107470
Kuhn Rj, Funk Je, Jenkins Rd, Permeability decay in CAVH hemofilters. Asaio Journal. ,vol. 34, pp. 590- 593 ,(1988)