Insulin counteraction of α-adrenergic effects on liver glycogen metabolism
作者： J MASSAGUE , J GUINOVART
DOI: 10.1016/0304-4165(78)90073-9
关键词:
摘要: Abstract Insulin counteracted the effects of a pure α-adrenergic agonist, phenylephrine, on heptocyte glycogen synthase and phosphorylase. These results argue against current concepts insulin increasing cytoplasmic Ca2+ concentration.
sci-hub.se 参考文章(16)
F D Assimacopoulos-Jeannet, P F Blackmore, J H Exton, Studies on alpha-adrenergic activation of hepatic glucose output. Studies on role of calcium in alpha-adrenergic activation of phosphorylase. Journal of Biological Chemistry. ,vol. 252, pp. 2662- 2669 ,(1977) , 10.1016/S0021-9258(17)40509-6
A D Cherrington, F D Assimacopoulos, J H Exton, J D Corbin, C R Park, S C Harper, Studies on the alpha-andrenergic activation of hepatic glucose output. II. Investigation of the roles of adenosine 3':5'-monophosphate and adenosine 3':5'-monophosphate-dependent protein kinase in the actions of phenylephrine in isolated hepatocytes. Journal of Biological Chemistry. ,vol. 251, pp. 5209- 5218 ,(1976) , 10.1016/S0021-9258(17)33148-4
Margaret E.M. Tolbert, Fred R. Butcher, John N. Fain, Lack of correlation between catecholamine effects on cyclic adenosine 3':5'-monophosphate and gluconeogenesis in isolated rat liver cells. Journal of Biological Chemistry. ,vol. 248, pp. 5686- 5692 ,(1973) , 10.1016/S0021-9258(19)43560-6
Enrique Belocopitow, Maria del Carmen Garcia Fernandez, Lutz Birnbaumer, Héctor N. Torres, Factors affecting muscle glycogen synthetase activity. IV. Comparative study of the different dependent forms of glycogen synthetase. Journal of Biological Chemistry. ,vol. 242, pp. 1227- 1231 ,(1967) , 10.1016/S0021-9258(18)96168-5
Y Takeda, J Larner, Structural studies on rabbit muscle glycogen synthase. II. Limited proteolysis. Journal of Biological Chemistry. ,vol. 250, pp. 8951- 8956 ,(1975) , 10.1016/S0021-9258(19)40677-7
T.M. Chan, J.H. Exton, alpha-Adrenergic-mediated accumulation of adenosine 3':5' monophosphate in calcium-depleted hepatocytes. Journal of Biological Chemistry. ,vol. 252, pp. 8645- 8651 ,(1977) , 10.1016/S0021-9258(19)75270-3
J N Fain, M J Birnbaum, Activation of protein kinase and glycogen phosphorylase in isolated rat liver cells by glucagon and catecholamines. Journal of Biological Chemistry. ,vol. 252, pp. 528- 535 ,(1977) , 10.1016/S0021-9258(17)32749-7
F T Brumley, F D Assimacopoulos, J H Exton, N J Hutson, S C Harper, Studies on the alpha-adrenergic activation of hepatic glucose output. I. Studies on the alpha-adrenergic activation of phosphorylase and gluconeogenesis and inactivation of glycogen synthase in isolated rat liver parenchymal cells. Journal of Biological Chemistry. ,vol. 251, pp. 5200- 5208 ,(1976) , 10.1016/S0021-9258(17)33147-2
G van de Werve, L Hue, H G Hers, Hormonal and ionic control of the glycogenolytic cascade in rat liver Biochemical Journal. ,vol. 162, pp. 135- 142 ,(1977) , 10.1042/BJ1620135
PETER SHERLINE, ALMORRIS LYNCH, WALTER H. GLINSMANN, Cyclic AMP and Aclrenergic Receptor Control of Rat Liver Glycogen Metabolism Endocrinology. ,vol. 91, pp. 680- 690 ,(1972) , 10.1210/ENDO-91-3-680