Signaling via Vascular Endothelial Growth Factor Receptors
作者： Tatiana V. Petrova , Taija Makinen , Kari Alitalo
关键词:
摘要: Angiogenesis, or development of blood vessels from preexisting vasculature, has important functions under both normal and pathophysiological conditions. Vascular endothelial growth factor receptors 1-3, also known as flt-1, KDR, flt-4, are cell-specific receptor tyrosine kinases which serve key mediators the angiogenic responses. The review focuses on signaling pathways that initiated these recently identified VEGF coreceptor neuroplilin-1.
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