Super-hydrophilic silicone hydrogels with interpenetrating poly(2-methacryloyloxyethyl phosphorylcholine) networks.
作者： Takanori Shimizu , Tatsuro Goda , Norihiko Minoura , Madoka Takai , Kazuhiko Ishihara
DOI: 10.1016/J.BIOMATERIALS.2010.01.026
关键词:
摘要: We synthesized silicone hydrogels from 2-methacryloyloxyethyl phosphorylcholine (MPC) and bis(trimethylsilyloxy)methylsilylpropyl glycerol methacrylate (SiMA) using two methods: random copolymerization with a small amount of cross-linker (P(SiMA-co-MPC)) construction an interpenetration network (IPN) structure composed cross-linked poly(MPC)(PMPC) chains poly(SiMA)(PSiMA) (PSiMA-ipn-PMPC). The polymerization was carried out by photoreaction. surface hydrophilicity water absorbability P(SiMA-co-MPC) increased increase in the MPC unit composition. On other hand, case PSiMA-ipn-PMPC, super-hydrophilic obtained enrichment units. optical mechanical properties PSiMA-ipn-PMPC are suitable for use as material preparing contact lenses. In addition, oxygen permeability remains high because PSiMA chains. units at reduce protein adsorption effectively. From these results we confirmed that it has potential application to hydrogel
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