Decreased lymphocyte transformation to vaccinia virus in multiple sclerosis

摘要: Lymphocyte transformation to vaccinia virus was measured in multiple sclerosis (MS) patients and normal controls. There a significant reduction of lymphocyte compared with the control group. In addition, positive correlation existed between degree disability extent presence virus. no cell-mediated immunity either serum or cerebrospinal fluid (CSF) antibody levels controls, all whom had been previously vaccinated. conjunction other studies, studies that have demonstrated elevated titers CSF patients, these results support possibility may play role pathogenesis sclerosis.