Elevated white blood cell count in subjects with Impaired glucose tolerance

作者: K. Ohshita , K. Yamane , M. Hanafusa , H. Mori , K. Mito

DOI: 10.2337/DIACARE.27.2.491

关键词:

摘要: OBJECTIVE —Impaired glucose tolerance (IGT) and impaired fasting (IFG) differ in their risk of all-cause cardiovascular mortality, but previous cross-sectional studies have suggested little difference levels lipids or blood pressure. We compared the white cell (WBC) count between subjects with IFG IGT. RESEARCH DESIGN AND METHODS —The were 4,720 nondiabetic Japanese men aged 24–84 years. Based on 75-g oral test, classified into following four groups: normal glucose/normal ( n = 3,753), isolated 290), IGT 476), IFG/IGT 201). WBC among groups investigated variables that showed a significant association count. RESULTS group had significantly higher than (6,530 vs. 6,210/mm 3 , P R 2 0.057). In analysis stratified by smoking status, was independently associated 2-h PG triglycerides, irrespective status. CONCLUSIONS —Individuals those IFG. The various components metabolic syndrome.

参考文章(33)
David W Brown, Wayne H Giles, Janet B Croft, White blood cell count: an independent predictor of coronary heart disease mortality among a national cohort. Journal of Clinical Epidemiology. ,vol. 54, pp. 316- 322 ,(2001) , 10.1016/S0895-4356(00)00296-1
Jawahar L Mehta, Tom G.P Saldeen, Kenneth Rand, Interactive role of infection, inflammation and traditional risk factors in atherosclerosis and coronary artery disease. Journal of the American College of Cardiology. ,vol. 31, pp. 1217- 1225 ,(1998) , 10.1016/S0735-1097(98)00093-X
Marek Straczkowski, Stella Dzienis-Straczkowska, Agnieszka Stêpieñ, Irina Kowalska, Malgorzata Szelachowska, Ida Kinalska, Plasma Interleukin-8 Concentrations Are Increased in Obese Subjects and Related to Fat Mass and Tumor Necrosis Factor-α System The Journal of Clinical Endocrinology and Metabolism. ,vol. 87, pp. 4602- 4606 ,(2002) , 10.1210/JC.2002-020135
Richard F. Gillum, Deborah D. Ingram, Diane M. Makuc, White blood cell count, coronary heart disease, and death: The NHANES I Epidemiologic Follow-up Study American Heart Journal. ,vol. 125, pp. 855- 863 ,(1993) , 10.1016/0002-8703(93)90181-8
Mitchell S Elkind, Jianfeng Cheng, Bernadette Boden-Albala, Myunghee C Paik, Ralph L Sacco, None, Elevated White Blood Cell Count and Carotid Plaque Thickness: The Northern Manhattan Stroke Study Stroke. ,vol. 32, pp. 842- 849 ,(2001) , 10.1161/01.STR.32.4.842
F. Corre, J. Lellouch, D. Schwartz, Smoking and leucocyte-counts The Lancet. ,vol. 298, pp. 632- 634 ,(1971) , 10.1016/S0140-6736(71)80071-5
T Murohara, M Buerke, A M Lefer, Polymorphonuclear leukocyte-induced vasocontraction and endothelial dysfunction. Role of selectins. Arteriosclerosis, Thrombosis, and Vascular Biology. ,vol. 14, pp. 1509- 1519 ,(1994) , 10.1161/01.ATV.14.9.1509
Andreas Festa, Ralph D’Agostino, George Howard, Leena Mykkänen, Russell P. Tracy, Steven M. Haffner, Chronic Subclinical Inflammation as Part of the Insulin Resistance Syndrome The Insulin Resistance Atherosclerosis Study (IRAS) Circulation. ,vol. 102, pp. 42- 47 ,(2000) , 10.1161/01.CIR.102.1.42
Edzard Ernst, Dale E Hammerschmidt, Ulf Bagge, Arpad Matrai, John A Dormandy, Leukocytes and the Risk of Ischemic Diseases JAMA. ,vol. 257, pp. 2318- 2324 ,(1987) , 10.1001/JAMA.1987.03390170074031