New Test-system Based on the Evaluation of Yeast Cells Resistance to Dehydration-rehydration Stress
作者： Diana Borovikova , Indrikis Muiznieks , Alexander Rapoport
DOI: 10.2174/1874070701509010049
关键词:
摘要: A new test-system was developed for rapid evaluation of the cytoprotective potential substances which can be included in cosmetics and health care compositions. It evaluated by changes viability yeast cells after dehydration/rehydration (D/R) treatment. To check efficiency proposed test system we studied effects water extracts natural peloid, are used balneotherapy procedures. revealed that resistance to D/R incubated peloid (PWE) significantly increased (by 30-38%) already their short incubation solutions with low concentrations PWE. Meanwhile membrane permeability decreased The were more sensitive stress PWE larger extent than initially resistant this stress. positive effect upon cell treatment linked stabilisation cells' plasma membrane. results obtained study indicate recommended as fast, simple cost-efficient assay various eukaryotic including also ingredients cosmetic products.
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