Paclitaxel cytotoxicity against human lung cancer cell lines increases with prolonged exposure durations.

作者: Edward K. Russell , Bruce E. Johnson , Adi F. Gazdar , Mark S. Georgiadis

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摘要: … exposed to a range of paclitaxel concentrations for durations of 3, 24, and 120 h, and cytotoxicity was measured with a tetrazolium-based assay… 28 cell lines at exposure durations of 3, …

参考文章(22)
L Gianni, C M Kearns, A Giani, G Capri, L Viganó, A Lacatelli, G Bonadonna, M J Egorin, Nonlinear pharmacokinetics and metabolism of paclitaxel and its pharmacokinetic/pharmacodynamic relationships in humans. Journal of Clinical Oncology. ,vol. 13, pp. 180- 190 ,(1995) , 10.1200/JCO.1995.13.1.180
E A Eisenhauer, W W ten Bokkel Huinink, K D Swenerton, L Gianni, J Myles, M E van der Burg, I Kerr, J B Vermorken, K Buser, N Colombo, European-Canadian randomized trial of paclitaxel in relapsed ovarian cancer: high-dose versus low-dose and long versus short infusion. Journal of Clinical Oncology. ,vol. 12, pp. 2654- 2666 ,(1994) , 10.1200/JCO.1994.12.12.2654
M S Georgiadis, B S Schuler, J E Brown, L V Kieffer, S M Steinberg, W H Wilson, C H Takimoto, M J Kelley, B E Johnson, Paclitaxel by 96-hour continuous infusion in combination with cisplatin : A phase I trial in patients with advanced lung cancer Journal of Clinical Oncology. ,vol. 15, pp. 735- 743 ,(1997) , 10.1200/JCO.1997.15.2.735
A D Seidman, D Hochhauser, M Gollub, B Edelman, T J Yao, C A Hudis, P Francis, D Fennelly, T A Gilewski, M E Moynahan, V Currie, J Baselga, W Tong, M O'Donaghue, R Salvaggio, L Auguste, D Spriggs, L Norton, Ninety-six-hour paclitaxel infusion after progression during short taxane exposure: a phase II pharmacokinetic and pharmacodynamic study in metastatic breast cancer. Journal of Clinical Oncology. ,vol. 14, pp. 1877- 1884 ,(1996) , 10.1200/JCO.1996.14.6.1877
J D Hainsworth, D S Thompson, F A Greco, Paclitaxel by 1-hour infusion: an active drug in metastatic non-small-cell lung cancer. Journal of Clinical Oncology. ,vol. 13, pp. 1609- 1614 ,(1995) , 10.1200/JCO.1995.13.7.1609
David R. Spriggs, Carlo Tondini, Taxol administered as a 120 hour infusion. Investigational New Drugs. ,vol. 10, pp. 275- 278 ,(1992) , 10.1007/BF00944181
Ruby M. Phelps, Bruce E. Johnson, Daniel C. Ihde, Adi F. Gazdar, David P. Carbone, Patrick R. McClintock, R. Ilona Linnoila, Mary J. Matthews, Paul A. Bunn, Desmond Carney, John D. Minna, James L. Mulshine, NCI-Navy Medical Oncology Branch cell line data base Journal of Cellular Biochemistry. ,vol. 63, pp. 32- 91 ,(1996) , 10.1002/JCB.240630505
Gi‐Ming Lai, Yi‐Nan Chen, Lyn A Mickley, Antonio T Fojo, Susan E Bates, None, P-glycoprotein expression and schedule dependence of adriamycin cytotoxicity in human colon carcinoma cell lines International Journal of Cancer. ,vol. 49, pp. 696- 703 ,(1991) , 10.1002/IJC.2910490512
James Liebmann, JohnA Cook, JamesB Mitchell, CREMOPHOR EL, SOLVENT FOR PACLITAXEL, AND TOXICITY The Lancet. ,vol. 342, pp. 1428- 1428 ,(1993) , 10.1016/0140-6736(93)92789-V
J Carmichael, JB Mitchell, WG DeGraff, J Gamson, AF Gazdar, BE Johnson, E Glatstein, JD Minna, Chemosensitivity testing of human lung cancer cell lines using the MTT assay. British Journal of Cancer. ,vol. 57, pp. 540- 547 ,(1988) , 10.1038/BJC.1988.125