The effects of vitamin D supplementation on proatherogenic inflammatory markers and carotid intima media thickness in subjects with metabolic syndrome: a randomized double-blind placebo-controlled clinical trial
作者： Abolhassan Shakeri Bavil , Hossein Mehralizadeh , Mohammad Asghari Jafarabadi , Aymaral Ghezel , Bahram Pourghassem Gargari
DOI: 10.1007/S12020-017-1317-2
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摘要: Metabolic syndrome may predispose to cardiovascular diseases. Since, in recent studies, vitamin D is advocated for cardioprotective roles, this study was designed investigate the effects of supplementation on proatherogenic inflammatory markers and common carotid intima media thickness subjects with metabolic syndrome. This randomized double blind clinical trial conducted Tabriz, Iran. Eligible (n = 80) were recruited thorough advertisement receive either (50,000 IU/week) or matching placebo 16 weeks. Interlukin-6, high sensitivity C-reactive protein, vascular cell adhesion molecule-1, E-selectin, measured at beginning end study. The registered http://www.irct.ir (code: IRCT201409033140N14). Sixteen weeks increased median serum 25-hydroxy [25(OH)D] mean calcium levels (p 0.05). Vitamin improved some No changes protein shown after
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