Protein Families: Relating Protein Sequence, Structure, and Function

摘要: New insights into the evolution and nature of proteinsExploring several distinct approaches, this book describes methods for comparing protein sequences structures in order to identify homologous relationships classify proteins domains evolutionary families. Readers will discover common features as well key philosophical differences underlying major classification systems, including Pfam, Panther, SCOP, CATH. Moreover, they'll how these systems can be used understand families predict degree which structural functional information are shared between relatives a family.Edited authored by leading international experts, Protein Families offers new that important medical research help us biological processes such cell signaling immune response. The is divided three sections: Section I: Concepts Underlying Family Classification reviews strategies identifying classifying them II: In-Depth Reviews focuses on some fascinating super we have substantial amounts sequence, data, making it possible trace emergence functionally diverse relatives. III: Review Important Biological Systems examines associated with particular theme, cytoskeleton.All chapters extensively illustrated, depictions relationships. References at end each chapter guide readers original papers field.Covering family alongside detailed descriptions select families, biochemists, molecular biologists, scientists, bioinformaticians insight proteins.