Planar strain analysis of liver undergoing microwave thermal ablation using x‐ray CT

作者: Noam Weiss , S. Nahum Goldberg , Yitzhak Nissenbaum , Jacob Sosna , Haim Azhari

DOI: 10.1118/1.4903896

关键词:

摘要: Purpose: To study the planar strain effects in liver during microwave (MW) thermal ablation as a means for tracking tissue expansion and contraction method improving monitoring. Methods: 1.4 mm circular metallic markers were inserted into 16 ex-vivo bovine fresh specimens, that subsequently ablated (with inside specimen) by 40 W of energy, 1, 2, 3, 6, 10 min. The tracked using an x-ray CT scanner. Images acquired every 5–10 s enabling determination markers’ coordinates over time. 2D principal strains calculated triangles formed subgroups three markers, their index, Ω, was plotted vs In addition, radial distance from antenna measured at end each ablation. Subsequently, sliced parallel to imaged planes zone traced digitized. average radius then computed compared distance. Results: strain, Ω(t), profile demonstrated ascending pattern until reaching maximum about 180 s, with mean peak value (Ω = 1.31 ± 0.04) indicating expansion. Thereafter, Ω progressively declined remaining duration treatment, contraction. Furthermore, when plotting size time time, it found two curves intercepted corresponding strain. Conclusions: By detecting point maximal tissues MW application, is possible noninvasively identify location front. fact proximal expands first part treatment contracts front reaches it, may serve index monitoring treatment.

参考文章(41)
Haim Azhari, James L. Weiss, Edward P. Shapiro, Distribution of Myocardial Strains: An MRI Study Advances in Experimental Medicine and Biology. ,vol. 382, pp. 319- 328 ,(1995) , 10.1007/978-1-4615-1893-8_31
S. Nahum Goldberg, G. Scott Gazelle, Peter R. Mueller, Thermal ablation therapy for focal malignancy: a unified approach to underlying principles, techniques, and diagnostic imaging guidance. American Journal of Roentgenology. ,vol. 174, pp. 323- 331 ,(2000) , 10.2214/AJR.174.2.1740323
Laura Farina, Noam Weiss, Yitzhak Nissenbaum, Marta Cavagnaro, Vanni Lopresto, Rosanna Pinto, Nevio Tosoratti, Claudio Amabile, Simone Cassarino, S. Nahum Goldberg, Characterisation of tissue shrinkage during microwave thermal ablation. International Journal of Hyperthermia. ,vol. 30, pp. 419- 428 ,(2014) , 10.3109/02656736.2014.957250
Erica M. Knavel, Christopher L. Brace, Tumor Ablation: Common Modalities and General Practices Techniques in Vascular and Interventional Radiology. ,vol. 16, pp. 192- 200 ,(2013) , 10.1053/J.TVIR.2013.08.002
Robert C. G. Martin, Charles R. Scoggins, Kelly M. McMasters, Safety and Efficacy of Microwave Ablation of Hepatic Tumors: A Prospective Review of a 5-Year Experience Annals of Surgical Oncology. ,vol. 17, pp. 171- 178 ,(2010) , 10.1245/S10434-009-0686-Z
T Varghese, J.A Zagzebski, F.T Lee, ELASTOGRAPHIC IMAGING OF THERMAL LESIONS IN THE LIVER IN VIVO FOLLOWING RADIOFREQUENCY ABLATION: PRELIMINARY RESULTS Ultrasound in Medicine and Biology. ,vol. 28, pp. 1467- 1473 ,(2002) , 10.1016/S0301-5629(02)00656-7
R. J. DeWall, T. Varghese, C. L. Brace, Quantifying Local Stiffness Variations in Radiofrequency Ablations With Dynamic Indentation IEEE Transactions on Biomedical Engineering. ,vol. 59, pp. 728- 735 ,(2012) , 10.1109/TBME.2011.2178848
Mannudeep K. Kalra, Michael M. Maher, Thomas L. Toth, Leena M. Hamberg, Michael A. Blake, Jo-Anne Shepard, Sanjay Saini, Strategies for CT Radiation Dose Optimization Radiology. ,vol. 230, pp. 619- 628 ,(2004) , 10.1148/RADIOL.2303021726
Jean-Baptiste Thibault, Ken D. Sauer, Charles A. Bouman, Jiang Hsieh, A three-dimensional statistical approach to improved image quality for multislice helical CT. Medical Physics. ,vol. 34, pp. 4526- 4544 ,(2007) , 10.1118/1.2789499
Willi A. Kalender, Heiko Wolf, Christoph Suess, Michael Gies, Holger Greess, Werner A. Bautz, Dose reduction in CT by on-line tube current control: principles and validation on phantoms and cadavers. European Radiology. ,vol. 9, pp. 323- 328 ,(1999) , 10.1007/S003300050674