The natural history of human immunodeficiency virus infection: a five year study in a London cohort of homosexual men.

摘要: Progression rates from asymptomatic to symptomatic Human Immunodeficiency Virus (HIV) infection according the CDC classification were prospectively studied in a cohort of 172 seropositive homosexual and bisexual men. The median follow-up time was 4 years. progression data entry study any group IV disease 56% (SE 7%) at 5 However, an estimated date seroconversion 36% 4%) This more than double rate AIDS-14% 3%) years calculated same way. There no differences AIDS A (systemic symptoms such as unexplained fever, weight loss or persistent diarrhoea) C-2 (oral candida oral hairy leukoplakia). significantly lower (p = 0.02) patients who under 25 age those over 25. review among cohorts shows that they tend be higher haemophiliac patients, early stage infection. when Pneumocystis carinii pneumonia is outcome measure, all studies are remarkably similar.