ISLET TRANSPLANTATION AND ANTIOXIDANT MANAGEMENT: A COMPREHENSIVE REVIEW
作者： Seyed Sajad Mohseni Salehi Monfared , Bagher Larijani , Mohammad Abdollahi
DOI: 10.3748/WJG.15.1153
关键词:
摘要: Islet transplantation as a promising treatment for type 1 diabetes has received widespread attention. Oxidative stress plays an essential role in cell injury during islet isolation and procedures. Antioxidants have been used various studies to improve The present study reviews the of oxidative benefits antioxidants bibliographical databases Pubmed Scopus were searched up November 2008. All relevant human animal in-vivo in-vitro studies, which investigated on islets, included. Almost all tested enhanced viability insulin secretion. Better control blood glucose after was major outcome antioxidant therapy studies. data also indicated that improved Although there is still insufficient evidence draw definitive conclusions about efficacy individual supplements, procedures cannot be ignored.
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