摘要: Recent years have seen a plethora of ideas and hypotheses, lots debate, about the origin evolution Hox gene cluster. Here I will attempt to summarize these identify their strengths weaknesses highlight types new data that may lead further resolution competing ideas. The major theme is genes originated very early in animal extensive independent duplications occurred lineages. Duplications however not been only route change composition structure cluster, as losses well. Indeed it loss one main obstacles our understanding clusters. Matters should be improved with wider taxon sampling along clearer how duplicated evolve.