Subacute sclerosing panencephalitis

作者: J. Joncas , G. Geoffroy , B. McLaughlin , G. Albert , N. Lapointe

DOI: 10.1016/0022-510X(74)90040-9

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摘要: Abstract Twelve new cases of subacute sclerosing panencephalitis were seen over a period 2 years in Montreal (and additional since the preparation this report) indicating high incidence (1.0 per million year) disease Province Quebec with total population 6 inhabitants. A history measles was obtained 10 and live attenuated vaccination other cases. Measles occurred at or under age 7 mean onset SSPE 7.3 years. few unusual observations made: (1) The finding EBV antibodies 8 tested, 5 which had titers above 1 80 ; (2) isolation and/or electron microscopy detection presumably latent herpes adenovirus 21 following co-cultivation biopsy autopsy material; (3) failure amantadine 3 to alter course disease.

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