tRNA anticodons with the modified nucleoside 2-methylthio-N6-(4-hydroxyisopentenyl)adenosine distinguish between bases 3' of the codon.
作者： Johanna U. Ericson , Glenn R. Björk
DOI: 10.1016/0022-2836(91)90697-5
关键词:
摘要: The modified nucleoside 2-methylthio-N6-(4-hydroxyisopentenyl)adenosine (ms2io6A) is present immediately to the 3′ side of anticodon (position 37) in tRNAs that read codons starting with uridine and hence include amber (UAG) suppressor tRNAs. We have used strains Salmonella typhimurium differ only their ability synthesize ms2io6A order determine specifically how this influences efficiency suppression two codon contexts differing by which base codon. results show presence not improves but also allows them distinguish between at least bases Thus, reduces intrinsic context sensitivity tRNA counteracts an unfavourable nucleotide on possible codon-anticodon interactions responsible for effect are discussed.
elsevier.com
sci-hub.se 参考文章(35)
H. Grosjean, H. Chantrenne, On Codon-Anticodon Interactions Chemical Recognition in Biology. ,vol. 32, pp. 347- 367 ,(1980) , 10.1007/978-3-642-81503-4_27
David Botstein, Ronald W. Davis, John R. Roth, Advanced bacterial genetics Cold Spring Harbor Laboratory. ,(1980)
E. Bubienko, P. Cruz, J.F. Thomason, P.N. Borer, Nearest-neighbor effects in the structure and function of nucleic acids. Progress in Nucleic Acid Research and Molecular Biology. ,vol. 30, pp. 41- 90 ,(1983) , 10.1016/S0079-6603(08)60683-2
Russell K. Chan, David Botstein, Tsutomu Watanabe, Yasuko Ogata, Specialized transduction of tetracycline resistance by phage P22 in Salmonella typhimurium: II. Properties of a high-frequency-transducing lysate Virology. ,vol. 50, pp. 883- 898 ,(1972) , 10.1016/0042-6822(72)90442-4
Henry J. Vogel, David M. Bonner, Acetylornithinase of Escherichia coli: partial purification and some properties. Journal of Biological Chemistry. ,vol. 218, pp. 97- 106 ,(1956) , 10.1016/S0021-9258(18)65874-0
Drew Smith, Michael Yarus, Transfer RNA structure and coding specificity: I. Evidence that a D-arm mutation reduces tRNA dissociation from the ribosome☆ Journal of Molecular Biology. ,vol. 206, pp. 489- 501 ,(1989) , 10.1016/0022-2836(89)90496-8
Tsutomu Watanabe, Yasuko Ogata, Russell K. Chan, David Botstein, Specialized transduction of tetracycline resistance by phage P22 in Salmonella typhimurium. I. Transduction of R factor 222 by phage P22. Virology. ,vol. 50, pp. 874- 882 ,(1972) , 10.1016/0042-6822(72)90441-2
M Yarus, S Cline, L Raftery, P Wier, D Bradley, The translational efficiency of tRNA is a property of the anticodon arm. Journal of Biological Chemistry. ,vol. 261, pp. 10496- 10505 ,(1986) , 10.1016/S0021-9258(18)67412-5
B A Castilho, P Olfson, M J Casadaban, Plasmid insertion mutagenesis and lac gene fusion with mini-mu bacteriophage transposons. Journal of Bacteriology. ,vol. 158, pp. 488- 495 ,(1984) , 10.1128/JB.158.2.488-495.1984
Timothy H. Tsang, Martin Buck, Bruce N. Ames, Sequence specificity of tRNA-modifying enzymes: An analysis of 258 tRNA sequences Biochimica et Biophysica Acta. ,vol. 741, pp. 180- 196 ,(1983) , 10.1016/0167-4781(83)90058-1