Multiresistance, beta-lactamase-encoding genes and bacterial diversity in hospital wastewater in Rio de Janeiro, Brazil.
作者： T.P.G. Chagas , L.M. Seki , J.C. Cury , J.A.L. Oliveira , A.M.R. Dávila
DOI: 10.1111/J.1365-2672.2011.05072.X
关键词:
摘要: Aims: To investigate the bacterial diversity, antimicrobial resistance patterns and types of beta-lactamase genes in Gram-negative bacteria isolated from a hospital sewage treatment plant. Methods Results: Between July December 2008, we collected samples influent, clarifier tank effluent chlorine contact plant service located city Rio de Janeiro, Brazil. Of 221 isolates identified, 40% were characterized as extended-spectrum (ESBL) producers. Nonpathogenic micro-organisms some pathogenic genera quantified. The most common ESBL-producing Klebsiella pneumoniae, Enterobacter cloacae Escherichia coli. blaTEM, blaSHV blaCTX-M detected 82, 48 67% isolates, respectively. Conclusions: Results showed that wastewater is not suitable systems for removal all antibiotic-resistant present wastewaters. Significance Impact Study: This study provides evidence resistant to multiple antibiotics their are usually can reach environment, even after use plants.
fiocruz.br参考文章(51)
Ashabil Aygan, Burhan Arikan, Resistance variations of third generation of Cephalosporins in some of the Enterobacteriaceae members in hospital sewage. International Journal of Agriculture and Biology. ,vol. 11, pp. 93- 96 ,(2009)
G E Murray, R S Tobin, B Junkins, D J Kushner, Effect of chlorination on antibiotic resistance profiles of sewage-related bacteria. Applied and Environmental Microbiology. ,vol. 48, pp. 73- 77 ,(1984) , 10.1128/AEM.48.1.73-77.1984
THOMAS H. JUKES, CHARLES R. CANTOR, CHAPTER 24 – Evolution of Protein Molecules Mammalian Protein Metabolism#R##N#Volume III. pp. 21- 132 ,(1969) , 10.1016/B978-1-4832-3211-9.50009-7
L Ovreås, L Forney, F L Daae, V Torsvik, Distribution of bacterioplankton in meromictic Lake Saelenvannet, as determined by denaturing gradient gel electrophoresis of PCR-amplified gene fragments coding for 16S rRNA. Applied and Environmental Microbiology. ,vol. 63, pp. 3367- 3373 ,(1997) , 10.1128/AEM.63.9.3367-3373.1997
Andrew Eaton, A.E. Greenberg, Lenore S. Clesceri, Standard methods for the examination of water and wastewater Published in <b>1998</b> in Washington DC) by American public health association. ,(1992)
Franz Ferdinand Reinthaler, Gebhard Feierl, Herbert Galler, Doris Haas, Eva Leitner, Franz Mascher, Angelika Melkes, Josefa Posch, Ingrid Winter, Gernot Zarfel, ESBL-producing E. coli in Austrian sewage sludge Water Research. ,vol. 44, pp. 1981- 1985 ,(2010) , 10.1016/J.WATRES.2009.11.052
Fernando Baquero, José-Luis Martínez, Rafael Cantón, Antibiotics and antibiotic resistance in water environments Current Opinion in Biotechnology. ,vol. 19, pp. 260- 265 ,(2008) , 10.1016/J.COPBIO.2008.05.006
Caio Fernando de Oliveira, Nara Lucia Frazzon Dal Forno, Izabel Almeida Alves, Jorge André Horta, Alexandre Rieger, Sydney Hartz Alves, Prevalence of the TEM, SHV and CTX-M families of extended-spectrum β-lactamases in Escherichia coli and Klebsiella spp at the University Hospital of Santa Maria, State of Rio Grande do Sul Revista Da Sociedade Brasileira De Medicina Tropical. ,vol. 42, pp. 556- 560 ,(2009) , 10.1590/S0037-86822009000500014
Simon D. Costanzo, John Murby, John Bates, Ecosystem response to antibiotics entering the aquatic environment Marine Pollution Bulletin. ,vol. 51, pp. 218- 223 ,(2005) , 10.1016/J.MARPOLBUL.2004.10.038
V. Jarlier, M.-H. Nicolas, G. Fournier, A. Philippon, Extended Broad-Spectrum β-Lactamases Conferring Transferable Resistance to Newer β-Lactam Agents in Enterobacteriaceae: Hospital Prevalence and Susceptibility Patterns Clinical Infectious Diseases. ,vol. 10, pp. 867- 878 ,(1988) , 10.1093/CLINIDS/10.4.867