5-HT receptors involved in initiation or modulation of motor patterns: Opportunities for drug development

摘要: Abstract A clearer understanding of the role descending systems in motor control can be achieved by using vitro preparations mammalian spinal cord that display patterned output, together with use selective pharmacological agents. It has been suggested 5-HT is involved either initiation or modulation certain behaviours, and it acts to enhance regulate pattern. Most attention paid locomotor rhythms underlying walking swimmig, respiratory pattern generation. In this article, David Wallis discusses involvement 1 , 2 receptors these processes possible therapeutic relevance.