Exercise and Brain Neurotransmission

摘要: Physical exercise influences the central dopaminergic, noradrenergic and serotonergic systems. A number of studies have examined brain noradrenaline (norepinephrine), serotonin (5-hydroxytryptamine; 5-HT) dopamine with exercise. Although there are great discrepancies in experimental protocols, results indicate that is evidence favour changes synthesis metabolism monoamines during There a possibility interactions between neurotransmitters their specific receptors could play role onset fatigue prolonged The data on effects branched chain amino acid (BCAA) supplementation 'central fatigue' seem to be conflicting, although recent suggest BCAA has no influence endurance performance. numerous levels at which can affect motor behaviour; from sensory perception, sensory-motor integration, effector mechanisms. However, crucial point whether or not neurotransmitter trigger reflect monoamine release. Until recently most were done homogenised tissue, gives indication dynamic release extracellular space living organisms. Recently, new techniques such as microdialysis voltammetry introduced measure vivo neurotransmitters. Microdialysis collect virtually any substance freely moving animal limited amount tissue trauma. This method allows measurement local on-going behavioural first using these methods influenced by few been published date show some discrepancies, we feel developed more sophisticated will improve our insight into relationship other transmitters Continued quantitative qualitative research needs conducted so further understanding neurotransmission gained.