Studies of the induction and maintenance of long-term graft acceptance by treatment with FK506 in heterotopic cardiac allotransplantation in rats.

摘要: Immunosuppressive activities of the newly discovered FK506, isolated from Streptomyces tsukubaensis, were examined by using cardiac allotransplantation in rat, and mechanisms underlying induction maintenance FK506-induced long-term allograft survival studied. Male rats WKA (RT