Metabolic disorders related to obesity and periodontal disease.

摘要: Being overweight and obese are important riskfactors for various adult diseases, including type 2diabetes, hyperlipemia, hypertension, cholelithiasis,arteriosclerosis, cardiovascular cerebro-vascular disease (31). Type 2 diabetes is rapidlybecoming prevalent in Japan the U.S.A. ismuch more common obese. Cardiovasculardisease most cause of death ac-counts than 17 million deaths annually. TheWorld Health Organization (WHO) estimated that 1billion people were [body mass index(BMI) > 25] or (BMI 30) 2005 thenumber will increase to 1.5 billion by 2015 if currenttrends continue (85). Although obesity was onceconsidered a health problem only wealthy coun-tries, WHO now states rising dra-matically poor intermediate countries. This isthe result number lifestyle-related factors,including global shift diet towards increasedenergy, fat, sugar intake, trend towardsdecreased physical activity because sedentarynature modern work transportation.Recently, has emerged as one riskindicators periodontal (Fig. 1A) con-versely, remote effects onvarious systemic diseases have been proposed(Fig. 2). Among disorders shownin Fig. 2, diseaseare established obesity-related (25, 31, 45,67). If true risk factor periodontaldisease, association among disease,obesity, diseasemust be very complex each confoundingfactor other. In addition, several studies havesuggested affects both glu-cose lipid metabolisms, which themselvesvery factors development bothtype disease. Consid-ering these issues, knowledge from recentreports must consolidated. The first part thisdocument reviews relationship between obesityand Then, it dis-cusses reports on influence diseaseon metabolic disorders, such metabolism, glucoseintolerance dyslipidemia.