Diaryl, dipyridinyl and aryl-pyridinyl derivatives and uses thereof

作者: Roger Benjamin Ruggeri , Benjamin Aaron Thuma , George Tetteh Magnus-Aryitey

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摘要: Compounds of Formula (I) that act as antagonists at the mu, kappa and/or delta opioid receptors and therefore useful in treatment diseases, conditions disorders benefit from such antagonism animals are described herein. where R, R1, R2a, R2b, R3, R4, V, R6, R7, R8, R9, W X

参考文章(74)
David A. Pfizer Global Res. Dev. Griffith, Philip A. Pfizer Global Res. Dev. Carpino, Robert Lee Pfizer Global Res. Dev. Dow, Bicyclic pyrazolyl and imidazolyl compounds and uses thereof ,(2004)
Karen A. Rossi, Donald J. P. Pinto, Lori L. Bostrom, Robert A. Galemmo, Nitrogen containing heteroaromatics with ortho-substituted P1's as factor Xa inhibitors ,(2001)
Hiromitsu Yokohama, Junichi Kamata, Daiya Shimokubo, Futoshi Miyazaki, Yoshinori Sakuma, Hidenori Seshimo, Yoshiaki Ohashi, Naoki Yoneda, Manabu Shirato, Yasutaka Takase, Mitsuaki Miyamoto, Ichiro Yoshida, Shuichi Suzuki, Nitrogen-containing condensed cyclic compound having a pyrazolyl group as a substituent group and pharmaceutical composition thereof ,(2002)
Scott D. Kuduk, Neville J. Anthony, Michael R. Wood, Mark G. Bock, Alpha-hydroxy amides as bradykinin antagonists or inverse agonists ,(2004)
Doo-Hee Park, Sung-Hack Lee, Myung-Gyun Kang, Kwang-Yul Moon, Sun-Hwa Lee, Eunice Eun-Kyeong Kim, Sang-Koo Lee, Hee-Dong Park, Oh-Hwan Kwon, Kwang-Yeon Hwang, Su-Kyung Park, Tae-Hee Lee, Jong-Woo Park, Yong-Seok Heo, Hye-Kyung Chang, Tae-Kyo Park, Factor xa inhibitors with aryl-amidines and derivatives, and prodrugs thereof ,(2001)
Erich Widmer, Dorothea Isler, Walter Rehm, Biomass lipase inhibitor useful for treating adiposity ,(1995)
Pasquale N. Confalone, Lynette May Oh, Philip Ma, Jiacheng Zhou, Hui-Yin Li, Synthesis of 1,3,5-trisubstituted pyrazoles ,(2001)