作者: Michael J. White , John M. Lopes , Susan A. Henry
DOI: 10.1016/S0065-2911(08)60004-1
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摘要: Because of its accessibility to genetic and molecular studies, Sacch. cerevisiae is an attractive organism in which pursue studies the complex roles phosphoinositides other inositol-containing metabolites. Biochemical have clearly demonstrated that PI, PIP, PIP2 inositol phosphates derived from them exist cerevisiae. It clear they are synthesized turned over following pathways similar those described higher eukaryotes. Recent on yeast also suggested phospholipids may play signalling detected animal cells. In addition, has been function as a global regulator phospholipid synthesis. This regulation occurs transcriptional level highly complex. not yet known whether inositol-mediated synthesis