Genetic characterization and transmitted drug resistance of the HIV type 1 epidemic in men who have sex with men in Beijing, China
作者： Lin Li , Na Han , Junfeng Lu , Tianyi Li , Xiangfu Zhong
关键词:
摘要: A rapid increase in the number of HIV cases men who have sex with (MSM) population has been observed China; however, little information is available on genetic characterization prevalent this population. In study, 95 HIV-1-seropositive drug-naive patients from Beijing MSM were enrolled. The and transmission drug resistance HIV-1 examined based full-length gag, pol, partial env gene sequences. Three subtypes, including CRF01_AE (56.0%), B (30.8%), CRF07_BC (12.6%), identified. Close phylogenetic relationships found among these strains isolates other populations Hebei province, which suggested that might act as a bridge for between high-risk populations. Drug-resistant mutations identified 5.3% sampled individuals. Our results provided detailed data would be helpful understanding transmitting pattern
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