Polarisability Anisotropy as an Indicator of the Effects of Aminoglycoside Antibiotics on Sensitive, Dependent and Resistant Strains of E.coli

作者: V. J. Morris , B. R. Jennings , N. J. Pearson , F. O’Grady

DOI: 10.1007/978-1-4684-3497-2_19

关键词:

摘要: Using high frequency, low amplitude pulsed electric fields, the anisotropy of electrical polarisability (△α) E.coli bacteria may be evaluated from scattered light intensity changes. △α has been found to very sensitive addition antibiotics aqueous suspensions. With increasing antibiotic concentration decreases in a manner reminiscent an adsorption isotherm. Illustrative data on interaction aminoglycoside with sensitive, dependent and two resistant strains K 12 is presented discussed.

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