Thermodynamics of RNA-RNA duplexes with 2- or 4-thiouridines: implications for antisense design and targeting a group I intron.

作者: Stephen M. Testa , Matthew D. Disney , Douglas H. Turner , Ryszard Kierzek

DOI: 10.1021/BI991187D

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摘要: Antisense compounds are designed to optimize selective hybridization of an exogenous oligonucleotide to a cellular target. Typically, Watson− Crick base pairing between the …

参考文章(1)
Wolfram Saenger, Principles of Nucleic Acid Structure ,(1983)