Comparison of seasonal serum 25-hydroxyvitamin D concentrations among pregnant women in Mongolia and Boston.

摘要: Abstract Adequate vitamin D status during pregnancy is important for developing fetal bone strength and density may play a role in preventing range of skeletal non-skeletal diseases both mothers children. We previously identified Mongolian women reproductive age to have the lowest levels yet observed any population globally, which renders this uniquely research. In study, we measured seasonal distribution 25-hydroxyvitamin (25(OH)D) concentration 390 healthy third trimester pregnant living urban rural Mongolia using DiaSorin LIAISON compared that 206 Boston, USA. Also, analyzed seasonally-independent associations between selected predictors groups quantile regression. Mean 25(OH)D were significantly higher less Boston (seasonal range: 27.1 ± 7.0–31.5 ± 7.7 ng/ml) than 11.2 ± 3.9–19.2 ± 6.7 ng/ml). Adjusting month blood draw, associated with older age, lower gravidity, BMI, lack college or university degree among participants, however, only gravidity was robust multivariable adjustment. No assessed characteristics independently predictive Mongolia, likely due universally low resulting between-person variation. conclusion, Mongolians severely depressed throughout year should be addressed through fortification supplementation, while U.S., deficiency specific targetable supplementation.