Hemovigilance network in France organization and analysis of immediate transfusion incident reports from 1994 to 1998

摘要: BACKGROUND : Hemovigilance networks have been introduced in several countries to improve knowledge of blood transfusion-related morbidity and mortality. The general organization the French network its results from 1994 through March 1999 are presented here. STUDY DESIGN AND METHODS hemovigilance relies on transfusion centers hospital correspondents, who analyze unexpected untoward effects transmit a Transfusion Incident Report (TIR) national database (Transfusion Reports Electronic Data Management [GIFIT]). RESULTS As 1, 1999, GIFIT contained 24,234 TIRs related incidents that occurred start until December 31, 1998. was not fully implemented 1996; but reporting rate seems since stabilized at approximately 7000 per year (2.5 reports 1000 components). highest is observed with platelet concentrates (4.02/1000), followed by RBCs (1.71/1000) FFP (0.34/1000). Bacterial contamination quickly appeared as major cause mortality (185 cases 18 fatalities). However, trend reduction this type incident over time, which can be attributed adoption preventive measures. In contrast, ABO mismatchings during RBC remained constant throughout period accounted for six fatalities. After implementation universal WBC reduction, some known WBCs, such nonhemolytic febrile reactions (NHFTR) HLA immunization, were dramatically reduced. CONCLUSION an important tool only incidents, also measure new processes or corrective actions level.