Robust hepatitis C virus infection in vitro
作者： J. Zhong , P. Gastaminza , G. Cheng , S. Kapadia , T. Kato
关键词:
摘要: The absence of a robust cell culture model hepatitis C virus (HCV) infection has severely limited analysis the HCV life cycle and development effective antivirals vaccines. Here we report establishment simple yet system based on JFH-1 molecular clone Huh-7-derived lines that allows production can be efficiently propagated in tissue culture. This provides powerful tool for host-virus interactions should facilitate discovery antiviral drugs vaccines this important human pathogen.
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