Effect of various doses of infective Toxocara canis and Toxocara cati eggs on the humoral response and distribution of larvae in mice.

摘要: The effect of 5–2,500 infectiveToxocara canis and 5–1,000T. cati eggs on the humoral immune response distribution larvae in organism was studied paratenic hosts — inbred C57BL6/J mice. With each dose ofT. maximal antibody level recorded day 56 post infection followed by a moderate decline that lasted until 154 experiment. A correlation between egg count observed only with infective 5–50 eggs. more rapid occurrence antibodies mice infected high In those given 5 7T. exceeded extinction threshold value from 21 to 84. Low doses (n=5) andT. (n=7) caused comparable mice, larval recoveries 70 ranged 10.00% 25.74%. Following 500T. eggs, 22.28% were recovered, although 1.08% localized brain. 1,000T. yielded, 36.37% larvae, as much 28.13% being found