Analysis of the Complete Genome of the Alkaliphilic and Phototrophic Firmicute Heliorestis convoluta Strain HHT

摘要: Despite significant interest and past work to elucidate the phylogeny photochemistry of species Heliobacteriaceae, genomic analyses heliobacteria date have been limited just one published genome, that thermophilic Heliobacterium (Hbt.) modesticaldum str. Ice1T. Here we present an analysis complete genome a second heliobacterium, Heliorestis (Hrs.) convoluta HHT, alkaliphilic, mesophilic, morphologically distinct heliobacterium isolated from Egyptian soda lake. The Hrs. is single circular chromosome 3.22 Mb with GC content 43.1% 3263 protein-encoding genes. In addition culture-based observations insights gleaned Hbt. enzyme-encoding genes key metabolic pathways supports obligately photoheterotrophic lifestyle for convoluta. A set encoding enzymes propionate butyrate catabolism absence gene lactate dehydrogenase distinguishes carbon metabolism its close relatives. Comparative proteins in convoluta, including cytochrome c553 Fo alpha subunit ATP synthase, those related reveal variations specific amino acid residues likely contribute success highly alkaline environment.