Annular phased-array high-intensity focused ultrasound device for image-guided therapy of uterine fibroids
作者： R.T. Held , V. Zderic , Thuc Nghi Nguyen , S. Vaezy
DOI: 10.1109/TUFFC.2006.1593372
关键词:
摘要: An ultrasound (US), image-guided high-intensity focused (HIFU) device was developed for noninvasive ablation of uterine fibroids. The HIFU an annular phased array, with a focal depth range 30-60 mm, natural focus 50 and resonant frequency 3 MHz. in-house control software to operate the electronics drive system inducing tissue coagulation at different distances from array. A novel imaging algorithm minimize HIFU-induced noise in US images. able produce lesions bovine serum albumin-embedded polyacrylamide gels excised pig liver. could be seen on images as hyperechoic regions. Depths ranging 30 60 mm were sonicated acoustic intensities 4100 6100 W/cm/sup 2/ 15 s each, latter producing average lesion volumes least 63% larger than former. Tissue sonication patterns that began distal transducer produced longer those proximally. variation dimensions indicates possible development protocols increase throughput shorten tumor treatment times.
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