The T3-induced gene KLF9 regulates oligodendrocyte differentiation and myelin regeneration

作者: Jason C. Dugas , Adiljan Ibrahim , Ben A. Barres

DOI: 10.1016/J.MCN.2012.03.007

关键词:

摘要: … for T3-induced OL differentiation, we next utilized siRNA to knock down KLF9 expression in … control non-targeting siRNAs (siControl), or a pool of siRNAs targeting KLF9 expression (…

参考文章(62)
Richard Reynolds, Mary Dawson, Dimitrios Papadopoulos, Annabella Polito, Isabelle Cenci di Bello, Danielle Pham-Dinh, Joel Levine, The response of NG2-expressing oligodendrocyte progenitors to demyelination in MOG-EAE and MS Journal of Neurocytology. ,vol. 31, pp. 523- 536 ,(2002) , 10.1023/A:1025747832215
Michael J. Malone, N.Paul Rosman, Maria Szoke, Donald Davis, Myelination of brain in experimental hypothyroidism Journal of the Neurological Sciences. ,vol. 26, pp. 1- 11 ,(1975) , 10.1016/0022-510X(75)90108-2
B.A. Barres, M.A. Lazar, M.C. Raff, A novel role for thyroid hormone, glucocorticoids and retinoic acid in timing oligodendrocyte development Development. ,vol. 120, pp. 1097- 1108 ,(1994) , 10.1242/DEV.120.5.1097
K. N. Scobie, B. J. Hall, S. A. Wilke, K. C. Klemenhagen, Y. Fujii-Kuriyama, A. Ghosh, R. Hen, A. Sahay, Krüppel-Like Factor 9 Is Necessary for Late-Phase Neuronal Maturation in the Developing Dentate Gyrus and during Adult Hippocampal Neurogenesis The Journal of Neuroscience. ,vol. 29, pp. 9875- 9887 ,(2009) , 10.1523/JNEUROSCI.2260-09.2009
A Rodriguez-Peña, N Ibarrola, M A Iñiguez, A Muñoz, J Bernal, Neonatal hypothyroidism affects the timely expression of myelin-associated glycoprotein in the rat brain. Journal of Clinical Investigation. ,vol. 91, pp. 812- 818 ,(1993) , 10.1172/JCI116301
Rakesh K. Gupta, Vijayalakshmi Bhatia, Harish Poptani, Ratni B. Gujral, Brain metabolite changes on in vivo proton magnetic resonance spectroscopy in children with congenital hypothyroidism The Journal of Pediatrics. ,vol. 126, pp. 389- 392 ,(1995) , 10.1016/S0022-3476(95)70454-X
L.-A. Harsan, J. Steibel, A. Zaremba, A. Agin, R. Sapin, P. Poulet, B. Guignard, N. Parizel, D. Grucker, N. Boehm, R. H. Miller, M. S. Ghandour, Recovery from Chronic Demyelination by Thyroid Hormone Therapy: Myelinogenesis Induction and Assessment by Diffusion Tensor Magnetic Resonance Imaging The Journal of Neuroscience. ,vol. 28, pp. 14189- 14201 ,(2008) , 10.1523/JNEUROSCI.4453-08.2008
Cecilia B. Marta, Ana M. Adamo, Eduardo F. Soto, Juana M. Pasquini, Sustained neonatal hyperthyroidism in the rat affects myelination in the central nervous system. Journal of Neuroscience Research. ,vol. 53, pp. 251- 259 ,(1998) , 10.1002/(SICI)1097-4547(19980715)53:2<251::AID-JNR14>3.0.CO;2-9
Pilar M.G. Pombo, Nieves Ibarrola, Miguel A. Alonso, Angeles Rodr�guez-Pe�a, Thyroid hormone regulates the expression of the MAL proteolipid, a component of glycolipid-enriched membranes, in neonatal rat brain Journal of Neuroscience Research. ,vol. 52, pp. 584- 590 ,(1998) , 10.1002/(SICI)1097-4547(19980601)52:5<584::AID-JNR10>3.0.CO;2-2
H Pei, Y Yao, Y Yang, K Liao, J-R Wu, Krüppel-like factor KLF9 regulates PPARγ transactivation at the middle stage of adipogenesis. Cell Death & Differentiation. ,vol. 18, pp. 315- 327 ,(2011) , 10.1038/CDD.2010.100