Increased activity of brain and platelet monoamine oxidase in dementia of Alzheimer type.
作者： R. Adolfsson , C-G. Gottfries , L. Oreland , Å. Wiberg , B. Winblad
DOI: 10.1016/0024-3205(80)90025-9
关键词:
摘要: Abstract Two groups of patients with dementia Alzheimer type were studied respect to monoamine oxidase (MAO) activity. In one group 11 MAO activity was determined in platelets and the other 14 brain (hypothalamus, caudate nucleus, hippocampus cortex gyrus cinguli) post mortem. The results compared controls matched for age sex. Platelet significantly higher controls. Brain MAO-B but not MAO-A hyppocampus cinguli. there positive correlations four regions, these absent group. This could be explained by differences onset that disease process does develop homogeneously different brains.
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